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Miosis is unpredictable, even in patients who do not have risk factors that can lead to surgical complications.2,3

Unplanned events can lead to a cascade of complications2,4-9

Miosis during cataract surgery can result in IFIS, inflammation pain, and CME

Despite your best efforts, miosis during cataract surgery can result in7,8,10:

The need for pupil expansion devices

More frequent surgical complications

Increased surgical time

IFIS is unpredictable2

  • Progressive intraoperative miosis, iris prolapse, or iris billowing can occur without warning during any stage of cataract surgery

Inflammation and pain can compromise your cataract surgery performance

Up to 35% of cataract surgery patients experience moderate to severe pain during the first hours after surgery

Intraoperative pain and irritation can impact patient satisfaction

  • 87% of patients reported intraoperative pain during second-eye surgery11

REFERENCES: 1. Visco D. Effect of phenylephrine/ketorolac on iris fixation ring use and surgical times in patients at risk of intraoperative miosis. Clin Ophthalmol. 2018;12:301-305. 2. Chang DF, Campbell JR, Colin J, Schweitzer C; the Study Surgeon Group. Prospective masked comparison of intraoperative floppy iris syndrome severity with tamsulosin versus alfuzosin. Ophthalmol. 2014;121(4):829-834. 3. Roach L. Strategies for preventing intraoperative miosis. EyeNet. June 2015:29-31. 4. Visco DM, Bedi R. Effect of intracameral phenylephrine 1.0%‑ketorolac 0.3% on postoperative cystoid macular edema, iritis, pain, and photophobia after cataract surgery. J Cataract Refract Surg. 2020;46(6):867-872. 5. Rosenberg ED, Nattis AS, Alevi D, et al. Visual outcomes, efficacy, and surgical complications associated with intracameral phenylephrine 1.0%/ketorolac 0.3% administered during cataract surgery. Clin Ophthalmol. 2018;12:21-28. 6. Al-Hashimi S, Donaldson K, Davidson R, et al. Medical and surgical management of the small pupil during cataract surgery. J Cataract Refract Surg. 2018;44(8):1032-1041. 7. Hovanesian JA, Sheppard JD, Trattler WB, et al. Intracameral phenylephrine and ketorolac during cataract surgery to maintain intraoperative mydriasis and reduce postoperative ocular pain: integrated results from 2 pivotal phase 3 studies. J Cataract Refract Surg. 2015;41:2060-2068. 8. Akman A, Yilmaz G, Oto S, Akova YA. Comparison of various pupil dilatation methods for phacoemulsification in eyes with a small pupil secondary to pseudoexfoliation. Ophthalmol. 2004;111:1693-1698. 9. Porela-Tiihonen S, Kaarniranta K, Kokki H. Postoperative pain after cataract surgery. J Cataract Refract Surg. 2013;39:789-798. 10. Osher RH, Ahmed IIK, Demopulos GA. OMS302 (phenylephrine and ketorolac injection) 1%/0.3% to maintain intraoperative pupil size and to prevent postoperative ocular pain in cataract surgery with intraocular lens replacement. Expert Rev Ophthalmol. 2015;10(2):91-103. 11. Jiang L, Zhang K, He W, Zhu X, Zhou P, Lu Y. Perceived pain during cataract surgery with topical anesthesia: a comparison between first-eye and second-eye surgery. J Ophthalmol. 2015;383456:1-6.